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Nutritional Supplement

Onion

  • Blood Sugar and Diabetes Support

    Type 2 Diabetes

    Onion may lower blood glucose levels and improve glucose tolerance in people with type 2 diabetes.
    Type 2 Diabetes
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    Onions have been used traditionally to treat diabetes. Animal studies suggest onion extracts may help reduce high blood glucose levels.23 Onion and its constituents have been shown in the laboratory to inhibit enzymes involved in the breakdown and digestion of starches and other carbohydrates, as well as enzymes involved in glucose metabolism.24,25 Onion has further been found to stimulate insulin responsiveness and glucose uptake by cells.26 Preliminary trials have found eating onions, in amounts of 60 and 100 grams (about 2 and 3.5 ounces) per day, lowered fasting blood glucose levels and the fasting response to glucose ingestion (glucose tolerance) in subjects with type 2 diabetes.27,28

    Type 1 Diabetes

    Research in laboratory animals suggests onion and its active constituents may lower blood glucose levels, raise insulin levels, reduce advanced glycation end-product (AGE) formation, and possibly prevent diabetes complications.
    Type 1 Diabetes
    ×
    Research in laboratory animals suggests onion and its active constituents may lower blood glucose levels, raise insulin levels, reduce advanced glycation end-product (AGE) formation, and possibly prevent diabetes complications.29,30,31 In one preliminary trial, people with type 1 diabetes had lower blood glucose levels four hours after eating about three ounces of raw onion than after receiving water.32
  • Immune System Support

    Cough

    Onion has a long history of use for relieving coughs.
    Cough
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    The mucilage of slippery elm gives it a soothing effect for coughs. Usnea also contains mucilage, which may be helpful in easing irritating coughs. There is a long tradition of using wild cherry syrups to treat coughs. Other traditional remedies to relieve coughs include bloodroot, catnip, comfrey (the above-ground parts, not the root), horehound, elecampane, mullein, lobelia, hyssop, licorice, mallow, (Malvia sylvestris),red clover, ivy leaf, pennyroyal (Hedeoma pulegioides, Mentha pulegium),onion, (Allium cepa), and plantain (Plantago lanceolata, P. major). None of these has been investigated in human trials, so their true efficacy for relieving coughs is unknown.

    Infection

    Onion is an herb that directly attack microbes.
    Infection
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    Herbs that directly attack microbes include the following: chaparral, eucalyptus, garlic, green tea, lemon balm (antiviral), lomatium, myrrh, olive leaf, onion, oregano, pau d’arco (antifungal), rosemary, sage, sandalwood, St. John’s wort, tea tree oil, thyme, and usnea.

  • Allergy and Lung Support

    Asthma

    Onion may act as an anti-inflammatory in people with asthma.
    Asthma
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    Onion may act as an anti-inflammatory in people with asthma. Human studies have shown onion can be a strong anti-inflammatory.33 However, some people with asthma may experience an exacerbation of symptoms if they are allergic to onion and are exposed to it.34

  • Skin Protection

    Eczema

    Onion injections into the skin and topical onion applications have been shown to inhibit skin inflammation in people with eczema, according to one trial.
    Eczema
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    Onion injections into the skin and topical onion applications have been shown to inhibit skin inflammation in people with eczema, according to one double-blind trial.35 The quantity or form of onion that might be most effective is unknown.

What Are Star Ratings?
×
Reliable and relatively consistent scientific data showing a substantial health benefit.
Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

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Traditional Use (May Not Be Supported by Scientific Studies)

Onion has been used as food for many centuries.36 Onion was also a popular folk remedy, being applied to tumors, made into a syrup for relieving coughs, or prepared in a tincture (using gin) to relieve “dropsy” (heart failure–related edema).37 It was considered a weaker version of garlic by many herbal practitioners. Like garlic, onion has a longstanding but unsubstantiated reputation as an aphrodisiac.36

References

1. Onstad D. Whole Foods Companion: A Guide for Adventurous Cooks, Curious Shoppers & Lovers of Natural Foods. White River Junction, VT: Chelsea Green Publishing Co, 1996:202-6.

2. Brodnitz MH, Pascale JV. Thiopropanal S-oxide: A lachrymatory [sic] factor in onions. J Agric Food Chem 1971;19:269-72.

3. Zohri AN, Abdel-Gawad K, Saber S. Antibacterial, antidermatophytic and antitoxigenic activities of onion (Allium cepa L.) oil. Microbiol Res 1995;150:167-72.

4. Kim JH. Anti-bacterial action of onion (Allium cepa L.) extracts against oral pathogenic bacteria. J Nihon Univ Sch Dent 1997;39:136-41.

5. Sharma KK, Gupta RK, Gupta S, Samuel KC. Antihyperglycemic effect of onion: Effect on fasting blood sugar and induced hyperglycemia in man. Indian J Med Res 1977;65:422-9.

6. Jain RC, Sachdev KN. A note on hypoglycemic action of onion in diabetes. Curr Med Pract 1971;15:901-2.

7. Mathew PT, Augusti KT. Hypoglycaemic effect of onion, Allium cepa Linn, on diabetes mellitus, a preliminary report. Indian J Physiol Pharmacol 1975;19:231-7.

8. Tjokroprawiro A, Pikir BS, Budhiarta AA, et al. Metabolic effects of onion and green beans on diabetic patients. Tohoku J Exp Med 1983;141:671–6.

9. Dorsch W, Ettl M, Hein G, et al. Anti-asthmatic effects of onions: inhibition of platelet-activating factor-induced bronchial construction by onion oils. Int Arch Allergy Appl Immunol 1987;82:535-6.

10. Dorsch W, Wagner H, Bayer T, et al. Antiasthmatic effects of onions: Alk(en)ylsulfinothic acid alk(en)ylesters inhibit histamine release, leukotriene and thromboxane biosynthesis in vitro and counteract PAF- and allergen-induced bronchial obstruction in vivo. Biochem Pharmacol 1988;37:4479-85.

11. Srivastava KC. Effect of onion and ginger consumption on platelet thromboxane production in humans. Prostaglandins Leukot Essent Fatty Acids 1989;35:183-5.

12. Dorsch W, Ring J. Suppression of immediate and late anti-IgE-induced skin reactions by topically applied alcohol/onion extract. Allergy 1984;39:43-9.

13. Chen JH, Chen HI, Tsai SJ, Jen CJ. Chronic consumption of raw but not boiled Welsh onion juice inhibits rat platelet function. J Nutr 2000;130:34-7.

14. Kendler BS. Garlic (Allium sativum) and onion (Allium cepa): A review of their relationship to cardiovascular disease. Prev Med 1987;16:670-85 [review].

15. Kleijnen J, Knipschild P, Ter Riet G. Garlic, onion and cardiovascular risk factors: A review of the evidence from human experiments with emphasis on commercially available preparations. Br J Clin Pharmacol 1989;28:535-44.

16. Hertog MGL, Feskens EJM, Hollman PCH, et al. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. Lancet 1993;342:1007-11.

17. Rimm EB, Katan MB, Ascherio A, et al. Relation between intake of flavonoids and risk for coronary heart disease in male health professionals. Ann Intern Med 1996; 125:384-9.

18. Louria DB, McAnally JF, Lasser N, et al. Onion extract in treatment of hypertension and hyperlipidemia: A preliminary communication. Curr Ther Res 1985;37:127-31.

19. Sharma KK, Chowdhury NK, Sharma AL, Misra MB. Studies on hypocholestraemic activity of onion. I. Effect on serum cholesterol in alimentary lipaemia in man. Indian J Nutr Diet 1975;12:288-91.

20. Dorant E, van der Brandt PA, Goldbohm RA, Sturmans F. Consumption of onions and a reduced risk of stomach carcinoma. Gastroenterology 1996;110:12-20.

21. Challier B, Perarnau JM, Viel JF. Garlic, onion and cereal fibre as protective factors for breast cancer: A French case-control study. Eur J Epidemiol 1998;14:737-47.

22. Dorant E, van den Brandt PA, Goldbohm RA. A prospective cohort study on the relationship between onion and leek consumption, garlic supplement use and the risk of colorectal carcinoma in the Netherlands. Carcinogenesis 1996;17:477-84.

23. Ikechukwu O, Ifeanyi O. The Antidiabetic Effects of The Bioactive Flavonoid (Kaempferol-3-O-beta-D-6{P- Coumaroyl} Glucopyranoside) Isolated from Allium cepa.Recent Pat Antiinfect Drug Discov 2016;11:44–52.

24. Oboh G, Ademiluyi A, Agunloye O, et al. Inhibitory Effect of Garlic, Purple Onion, and White Onion on Key Enzymes Linked with Type 2 Diabetes and Hypertension. J Diet Suppl 2019;16:105–18.

25. Akash M, Rehman K, Chen S. Spice plant Allium cepa: dietary supplement for treatment of type 2 diabetes mellitus. Nutrition 2014;30:1128–37.

26. Gautam S, Pal S, Maurya R, Srivastava A. Ethanolic extract of Allium cepa stimulates glucose transporter typ 4-mediated glucose uptake by the activation of insulin signaling. Planta Med 2015;81:208–14.

27. Taj Eldin I, Ahmed E, Elwahab H. Preliminary Study of the Clinical Hypoglycemic Effects of Allium cepa (Red Onion) in Type 1 and Type 2 Diabetic Patients. Environ Health Insights 2010;4:71–7.

28. Tjokroprawiro A, Pikir BS, Budhiarta AA, et al. Metabolic effects of onion and green beans on diabetic patients. Tohoku J Exp Med 1983;141:671–6.

29. Pradeep S, Srinivasan K. Amelioration of hyperglycemia and associated metabolic abnormalities by a combination of fenugreek (Trigonella foenum-graecum) seeds and onion (Allium cepa) in experimental diabetes. J Basic Clin Physiol Pharmacol 2017;28:493–505.

30. Abouzed T, Contreras M, Sadek K, et al. Red onion scales ameliorated streptozotocin-induced diabetes and diabetic nephropathy in Wistar rats in relation to their metabolite fingerprint. Diabetes Res Clin Pract 2018;140:253–64.

31. Ikechukwu O, Ifeanyi O. The Antidiabetic Effects of The Bioactive Flavonoid (Kaempferol-3-O-beta-D-6{P- Coumaroyl} Glucopyranoside) Isolated from Allium cepa.Recent Pat Antiinfect Drug Discov 2016;11:44–52.

32. Taj Eldin I, Ahmed E, Elwahab H. Preliminary Study of the Clinical Hypoglycemic Effects of Allium cepa (Red Onion) in Type 1 and Type 2 Diabetic Patients. Environ Health Insights 2010;4:71–7.

33. Dorsch W, Ettl M, Hein G, et al. Anti-asthmatic effects of onions: inhibition of platelet-activating factor-induced bronchial construction by onion oils. Int Arch Allergy Appl Immunol 1987;82:535-6.

34. Valdivieso R, Subiza J, Varela-Losada S, et al. Bronchial asthma, rhinoconjunctivitis, and contact dermatitis caused by onion. J Allergy Clin Immunol 1994;94:928-30.

35. Dorsch W, Ring J. Suppression of immediate and late anti-IgE-induced skin reactions by topically applied alcohol/onion extract. Allergy 1984;39:43-9.

36. Onstad D. Whole Foods Companion: A Guide for Adventurous Cooks, Curious Shoppers & Lovers of Natural Foods. White River Junction, VT: Chelsea Green Publishing Co, 1996:202-6.

37. Felter HW, Lloyd JU. King's American Dispensatory, 18th ed, vol 1. Portland, OR: Eclectic Medical Publications, 1898, 1983:146.

38. Tjokroprawiro A, Pikir BS, Budhiarta AA, et al. Metabolic effects of onion and green beans on diabetic patients. Tohoku J Exp Med 1983;141:671–6.

39. Jain RC, Sachdev KN. A note on hypoglycemic action of onion in diabetes. Curr Med Pract 1971;15:901-2.

40. Bordia T, Mohammed N, Thomson M, Ali M. An evaluation of garlic and onion as antithrombotic agents. Prostaglandins Leukot Essent Fatty Acids 1996;54:183-6.

41. Chen JH, Chen HI, Tsai SJ, Jen CJ. Chronic consumption of raw but not boiled Welsh onion juice inhibits rat platelet function. J Nutr 2000;130:34-7.

42. Ali M, Bordia T, Mustafa T. Effect of raw versus boiled aqueous extract of garlic and onion on platelet aggregation. Prostaglandins Leukot Essent Fatty Acids 1999;60:43-7.

43. Allen ML, Mellow MH, Robinson MG, Orr WC. The effect of raw onions on acid reflux and reflux symptoms. Am J Gastroenterol 1990;85:377-80.

44. Valdivieso R, Subiza J, Varela-Losada S, et al. Bronchial asthma, rhinoconjunctivitis, and contact dermatitis caused by onion. J Allergy Clin Immunol 1994;94:928-30.

45. Wuensch KL. Exposure to onion taste in mother's milk leads to enhanced preference for onion diet among weanling rats. J Gen Psychol 1978;99(2d Half):163-7.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.