My Cart Find A Store

Nutritional Supplement

PABA

Also indexed as:Para-Aminobenzoic Acid

  • Women's Health

    Female Infertility

    Some women have achieved pregnancy after supplementing with PABA, which is believed to increase the ability of estrogen to facilitate fertility.
    Female Infertility
    ×
     

    Some previously infertile women have become pregnant after supplementing with PABA (para-aminobenzoic acid), 100 mg four times per day.1 PABA is believed to increase the ability of estrogen to facilitate fertility.

  • Skin Protection

    Dermatitis Herpetiformis

    PABA in high amounts has been reported to reduce or eliminate the skin lesions of DH in one preliminary trial.
    Dermatitis Herpetiformis
    ×
     

    Para-aminobenzoic acid (PABA) in high amounts (9–24 grams per day) has been reported to reduce or eliminate the skin lesions of DH in one preliminary, clinical trial.2 With continued administration, people with DH remained symptom-free for as long as 30 months. Since supplementation with such large amounts of PABA has the potential to cause side effects, these amounts should be used only with medical supervision.

    Vitiligo

    PABA, a compound commonly found in B-complex vitamins, has been shown to repigment skin affected by vitiligo.
    Vitiligo
    ×
     

    An early report described the use of PABA (para-aminobenzoic acid)—a compound commonly found in B-complex vitamins—for vitiligo. Consistent use of 100 mg of PABA three or four times per day, along with an injectable form of PABA and a variety of hormones tailored to individual needs, resulted, in many cases, in repigmentation of areas affected by vitiligo.3

What Are Star Ratings?
×
Reliable and relatively consistent scientific data showing a substantial health benefit.
Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

Temp Title
×
Temp Text

References

1. Sieve BF. The clinical effects of a new B-complex factor, para-aminobenzoic acid, on pigmentation and fertility. South Med Surg 1942;104:135-9.

2. Zarafonetis CJ, Johnwick EB, Kirkman LW, Curtis AC. Paraaminobenzoic acid in dermatitis herpetiformis. Arch Dermatol Syph 1951;63:115-32.

3. Sieve BF. Further investigations in the treatment of vitiligo. Virginia Med Monthly 1945;Jan:6-17.

4. Kantor GR, Ratz JL. Liver toxicity from potassium para-aminobenzoate. J Am Acad Dermatol 1985;13:671-2.

5. Hughes CG. Oral PABA and vitiligo. J Am Acad Dermatol 1983;9:770 [letter].

6. Worobec S, LaChine A. Dangers of orally administered para-aminobenzoic acid. JAMA 1984;251:2348.

7. Zarafonetis CJD, Grekin RH, Curtis AC, et al. Further studies on the treatment of lupus erythematosus with sodium para-aminobenzoate. J Invest Dermatol 1948;11:359.

Copyright © 2025 TraceGains, Inc. All rights reserved.

Learn more about TraceGains, the company.

The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.