Nutritional Supplement
Pregnenolone
Where to Find It
The cells of both the adrenal gland and the central nervous system synthesize pregnenolone. Human studies show there are much higher concentrations of pregnenolone in the nervous tissue, than in the bloodstream.2 Animal studies indicate the concentration of pregnenolone in the brain is ten-fold higher than that of other stress-related hormones (including DHEA).3 Pregnenolone is present in the blood as both free pregnenolone and a more stable form, pregnenolone-sulfate.
How to Use It
Pregnenolone is generally available in amounts of 10 to 30 mg. It is not known what an appropriate intake is for humans or whether the benefits of taking this hormone outweigh the risks.