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Nutritional Supplement

Royal Jelly

  • Heart and Circulatory Health

    High Cholesterol

    Supplementing with royal jelly may improve cholesterol levels.
    High Cholesterol
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    Royal jelly contains various sugars, proteins, and medium-chain fatty acids and has demonstrated antioxidant and anti-inflammatory properties. Royal jelly was found to lower total, LDL-, and non-HDL cholesterol levels in subjects with type 2 diabetes in a meta-analysis of findings from 12 randomized controlled trials.1 In a placebo-controlled trial in 40 subjects with mildly elevated cholesterol levels, 3,150 mg royal jelly daily resulted in an 11.5% reduction in total cholesterol levels and a 4.8% reduction in LDL-cholesterol levels.2 In an eight-week placebo-controlled trial with 60 healthy overweight participants, 666 mg of royal jelly per day was found to lower total cholesterol levels and improve antioxidant status.3 A small controlled trial in 15 healthy volunteers found 6 grams of royal jelly per day for four weeks reduced total and LDL-cholesterol levels.4 In an uncontrolled trial, 36 healthy postmenopausal women received 150 mg of a high-potency royal jelly product daily for three months; at the end of the trial, HDL-cholesterol levels had increased by 7.7%, total cholesterol levels had decreased by 3.09 %, and LDL-cholesterol levels had decreased by 4.1%.5
What Are Star Ratings?
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Reliable and relatively consistent scientific data showing a substantial health benefit.
Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

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References

1. Maleki V, Jafari-Vayghan H, Saleh-Ghadimi S, et al. Effects of Royal jelly on metabolic variables in diabetes mellitus: A systematic review. Complement Ther Med 2019;43:20–7.

2. Chiu HF, Chen BK, Lu YY, et al. Hypocholesterolemic efficacy of royal jelly in healthy mild hypercholesterolemic adults. Pharm Biol 2017;55:497–502.

3. Petelin A, Kenig S, Kopinč R, et al. Effects of Royal Jelly Administration on Lipid Profile, Satiety, Inflammation, and Antioxidant Capacity in Asymptomatic Overweight Adults. Evid Based Complement Alternat Med 2019;2019:4969720.

4. Guo H, Saiga A, Sato M, et al. Royal jelly supplementation improves lipoprotein metabolism in humans. J Nutr Sci Vitaminol (Tokyo) 2007;53:345–8.

5. Lambrinoudaki I, Augoulea A, Rizos D, et al. Greek-origin royal jelly improves the lipid profile of postmenopausal women. Gynecol Endocrinol 2016;32:835–9.

6. Thien FCK, Leung R, Baldo BA, et al. Asthma and anaphylaxis induced by royal jelly. Clin Exp Allergy 1996;26:216–22.

7. Leung R, Ho A, Chan J, et al. Royal jelly consumption and hypersensitivity in the community. Clin Exp Allergy 1997;27:333–6.

8. Yonei Y, Shibagaki K, Tsukada N, et al. Case report: haemorrhagic colitis associated with royal jelly intake. J Gastroenterol Hepatol 1997;12:495–9.

9. Takahashi M, Matsuo I, Ohkido M. Contact dermatitis due to honeybee royal jelly. Contact Dermatitis 1983;9:452–5.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.