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Nutritional Supplement

Schisandra

Also indexed as:Schisandra chinensis, Schizandra

  • Explanation Required

    3

    • Schisandra

      Acetaminophen

      Needs Explanation

      Gomisin A is a constituent found in the Chinese herb schisandra (Schisandra chinensis). In a study of rats given liver-damaging amounts of acetaminophen, gomisin A appeared to protect against some liver damage but did not prevent glutathione depletion (unlike milk thistle, as reported above). Studies have not yet confirmed this action in humans.

      Acetaminophen
      Schisandra
      ×
      1. Yamada S, Murawaki Y, Kawasaki H. Preventive effect of gomisin A, a lignan component of schizandra fruits, on acetaminophen-induced hepatotoxicity in rats. Biochem Pharmacol 1993;46:1081-5.

    • Schisandra

      Acetaminophen with Codeine

      Needs Explanation

      Gomisin A is a constituent found in the Chinese herb schisandra(Schisandra chinensis). In a study of rats given liver-damaging amounts of acetaminophen, gomisin A appeared to protect against some liver damage but did not prevent glutathione depletion (unlike milk thistle, as reported above). Studies have not yet confirmed this action in humans.

      Acetaminophen with Codeine
      Schisandra
      ×
      1. Yamada S, Murawaki Y, Kawasaki H. Preventive effect of gomisin A, a lignan component of schizandra fruits, on acetaminophen-induced hepatotoxicity in rats. Biochem Pharmacol 1993;46:1081-5.

    • Schisandra

      Hydrocodone-Acetaminophen

      Needs Explanation

      Gomisin A is a constituent found in the Chinese herb schisandra(Schisandra chinensis). In a study of rats given liver-damaging amounts of acetaminophen, gomisin A appeared to protect against some liver damage but did not prevent glutathione depletion (unlike milk thistle, as reported above). Studies have not yet confirmed this action in humans.

      Hydrocodone-Acetaminophen
      Schisandra
      ×
      1. Yamada S, Murawaki Y, Kawasaki H. Preventive effect of gomisin A, a lignan component of schizandra fruits, on acetaminophen-induced hepatotoxicity in rats. Biochem Pharmacol 1993;46:1081-5.

References

1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, 2d ed. New York: John Wiley & Sons, 1996, 469-72.

2. Liu KT. Studies on fructus Schisandrae chinensis. Annex 12: Studies on fructus Schisandrae chinensis. Plenary lecture, World Health Organization Seminar on the Use of Medicinal Plants in Health Care, Sept 1977, Tokyo, Japan. In: WHO Regional Office for the Western Pacific Final Report, Manila, 1977, 101-12.

3. Chang HM, But P (eds). Pharmacology and Applications of Chinese Materia Medica 1. Singapore: World Scientific, 1986.

4. Ip SP, Poon MKT, Wu SS, et al. Effect of schisandrin B on hepatic glutathione antioxidant system in mice: Protection against carbon tetrachloride toxicity. Planta Med 1995;61:398-401.

5. Park JY, Kim KH. A randomized, double-blind, placebo-controlled trial of Schisandra chinensis for menopausal symptoms. Climacteric 2016;19:574–80.

6. Park JY, Kim KH. A randomized, double-blind, placebo-controlled trial of Schisandra chinensis for menopausal symptoms. Climacteric 2016;19:574–80.

7. Scaglione F, Cattaneo G, Alessandria M, Cogo R. Efficacy and safety of the standardized ginseng extract G 115 for potentiating vaccination against common cold and/or influenza syndrome. Drugs Exp Clin Res 1996;22:65-72.

8. Westphal J, Hörning M, Leonhardt K. Phytotherapy in functional upper abdominal complaints. Results of a clinical study with a preparation of several plants. Phytomedicine 1996;2:285-91.

9. Baba S, Takasaka T. Double-blind clinical trial of sho-seiryu-to (TJ-19) for perennial nasal allergy. Clin Otolaryngol 1995;88:389-405.

10. Foster S, Yue CX. Herbal Emissaries: Bringing Chinese Herbs to the West. Rochester, VT: Healing Arts Press, 1992, 146-52.

11. Shu HY. Oriental Materia Medica: A Concise Guide. Palos Verdes, CA: Oriental Healing Arts Press, 1986, 624-5.

12. Foster S, Yue CX. Herbal Emissaries: Bringing Chinese Herbs to the West. Rochester, VT: Healing Arts Press, 1992, 146-52.

13. McGuffin M, Hobbs C, Upton R, et al. American Herbal Product Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, 1997, 104.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.