Desiccated thyroid, also called thyroid extract (e.g., Armour Thyroid), is used by some doctors as an alternative to synthetic thyroid hormones (such as thyroxine [Synthroid or other brand names]) for people with hypothyroidism. Thyroid extract contains two biologically active hormones (thyroxine and triiodothyronine), whereas the most commonly prescribed thyroid-hormone preparations contain only thyroxine. One study has shown that the combination of the two hormones contained in desiccated thyroid is more effective than thyroxine alone for those with hypothyroidism.¹ One doctor reported that thyroid extract worked better than standard thyroid preparations for many of his patients with hypothyroidism.² Glandular thyroid products, which are available from health food stores, have had most of the thyroid hormone removed and would therefore not be expected to be effective for people with hypothyroidism. Intact desiccated thyroid is available only by prescription. Hypothyroidism sufferers who want to use desiccated thyroid must first consult with a physician.