See also Warning section.

Read the Medication Guide provided by your pharmacist before you start taking edoxaban and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor, usually once daily. The dosage is based on your medical condition, weight, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

If you have trouble swallowing the tablet whole, you may crush the tablet and mix it with 2 to 3 ounces (60 to 90 milliliters) of water or applesauce. Drink or eat the entire mixture right away. Do not prepare a supply for future use.

If you are giving this medication through a tube into the stomach (gastric tube), ask your health care professional for detailed instructions on how to properly mix and give it.

Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.