See also Warning section.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

If you also take "triptan" migraine drugs (such as sumatriptan, rizatriptan), you will need to separate your triptan dose from your dose of this medication to lessen the chance of serious side effects. Ask your doctor how long you should wait between your doses of these drugs.

Some products may contain caffeine or ingredients that could raise your heart rate or blood pressure. Certain beverages (such as coffee, colas, energy drinks) may also contain caffeine. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or other headache products).

This medication may interfere with certain medical/lab tests (such as dipyridamole-thallium imaging tests, urine catecholamine/5-HIAA levels), possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.