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Galsulfase

Pronounced

"gal-SUL-fase"

Common brand names:

Naglazyme

Uses

Galsulfase is used to treat a certain rare genetic problem (Maroteaux-Lamy syndrome - MLS). Galsulfase replaces a certain natural substance that is missing in people with MLS.

This medication improves how far you can walk and the number of stairs you can climb up. Galsulfase does not correct the genetic problem, and treatment must be continued for life.

How to Use This Medication

This medication is given by injection into a vein by a health care professional. It is given as directed by your doctor, usually once a week. It is injected slowly into a vein over 4 hours. The dosage is based on your weight, medical condition, and response to treatment.

Infusion reactions may happen during the infusion of this drug. Your doctor may prescribe other medications (such as antihistamines, drugs for fever) before each treatment to help prevent these side effects. Tell your doctor right away if you have any symptoms of infusion reactions such as fever, chills, shortness of breath, nausea/vomiting, increased blood pressure, headache, chest pain, dizziness, weakness/tiredness, joint pain, flushing, or coughing. Your doctor may give you other medications to help with these side effects or may slow down or stop your treatment for some time.

Use this medication regularly to get the most benefit from it. To help you remember, use it on the same day each week.

Tell your doctor if your condition gets worse.