This medication is given by injection into a vein by a health care professional. It is injected slowly into a vein over 1 to 2 hours as directed by your doctor. The dosage and how often it is given depends on your weight, medical condition, and response to treatment. Follow your doctor's directions carefully.

Infusion reactions may happen during the infusion of this drug and for a short time afterward. Tell your doctor right away if you have symptoms of infusion reactions such as shortness of breath, cough, flushing, dizziness, or fast heartbeat. Your doctor may give you other medications to help with these side effects or may slow down or stop your treatment for some time.

Tell your doctor if your condition lasts or gets worse. Blood, liver, and spleen problems usually improve in the first year of treatment. It may take 2 to 3 years of treatment to see the full benefit to your bones.