Take this medication by mouth with or without food as directed by your doctor, usually once daily in the morning. If you take this drug too close to bedtime, you may need to wake up to urinate. It is best to take this medication at least 4 hours before your bedtime.

The dosage is based on your medical condition and response to treatment.

Take this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time each day. Keep taking this medication even if you feel well. Most people with high blood pressure do not feel sick. It may take up to several weeks before you get the full benefit of this drug.

If you also take certain drugs to lower your cholesterol (bile acid-binding resins such as cholestyramine or colestipol), take indapamide at least 4 hours before or at least 4 hours after these medications.

Tell your doctor if your condition does not get better or if it gets worse (for example, your blood pressure readings remain high or increase).