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Methotrexate

This form:
What Are Nutrient Interactions
Types of interactions:beneficial= Beneficialadverse= Adversecheck= Check
dnicon_BeneficialReplenish Depleted Nutrients
Magnesium and Potassium
Calcium
Glutathione
Lactobacillus GG
N-Acetyl Cysteine
Phosphate
Retinoic Acid
Spleen Peptide Extract
Taurine
Vitamin K3
dnicon_BeneficialReduce Side Effects
Acetyl-L-Carnitine
Calcium and Magnesium
Glutamine
Glutathione
Melatonin
Probiotics
Selenium
Vitamin E
Wheat Grass
Beta-Carotene
Chamomile
Eleuthero
Ginger
Spleen Peptide Extract
Zinc
dnicon_BeneficialSupport Medicine
Thymus Extracts
Wheat Grass
Melatonin
Milk Thistle
PSK
dnicon_AvoidReduces Effectiveness

none

dnicon_AvoidPotential Negative Interaction
PABA
dnicon_CheckExplanation Required
Folic Acid
Vitamin A
Antioxidants
Echinacea
Multivitamin
N-Acetyl Cysteine
Vitamin A, Vitamin C, and N-Acetyl Cysteine
Vitamin C
The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the Uses and Precautions tabs or the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

Drug Interactions

See also Warning section.

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.

Some products that may interact with this drug include: acitretin, asparaginase, chloramphenicol, leflunomide, other drugs that can cause kidney problems (such as cisplatin), other drugs that can cause liver problems (such as azathioprine, sulfasalazine, retinoids such as isotretinoin), penicillins, phenytoin, probenecid, procarbazine, pyrimethamine, sulfa medications, tetracyclines.

Certain drugs that reduce stomach acid (proton pump inhibitors-PPIs such as esomeprazole, omeprazole, pantoprazole) may increase the amount of methotrexate in your blood. This effect may increase the risk of side effects, especially with high-dose methotrexate treatment. Ask your doctor or pharmacist for details and ways to lessen the risk of side effects.