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Natalizumab

Pronounced

"nay-tal-IZ-oo-mab"

Common brand names:

Tysabri

Uses

Natalizumab is used to treat multiple sclerosis-MS. It is not a cure for MS, but it is thought to help by preventing your immune system from attacking the nerves in your brain and spinal cord. It helps decrease the number of episodes of worsening symptoms and may prevent or delay disability. Natalizumab is also used to treat a bowel condition called Crohn's disease (CD). It is not a cure for CD, but it is thought to work by preventing your immune system from causing inflammation/swelling within your bowels. Natalizumab is a protein called a monoclonal antibody.

How to Use This Medication

Read the Medication Guide provided by your pharmacist before you start using natalizumab and each time you receive another dose. If you have any questions, ask your doctor or pharmacist.

This medication is given by injection into a vein by a health care professional as directed by your doctor, usually every 4 weeks. This medication is usually given over 1 hour.

Infusion reactions may happen during the infusion of this drug and for a short time afterward. Tell your doctor right away if you have any symptoms of infusion reactions such as chills, fever, flushing, nausea, dizziness, tiredness, or chest pain.

It is important to use this medication regularly to get the most benefit from it. Do not miss any doses without your doctor's approval.

Tell your doctor if your condition worsens. When using this medication for Crohn's disease, if your condition does not improve after 12 weeks of treatment, your doctor will need to switch your treatment plan.