Read the Patient Information Leaflet if available from your pharmacist before you start using nelfinavir and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with a meal as directed by your doctor, usually 2 to 3 times daily.

If you are unable to swallow tablets, you may crush your dose and take it with food. The tablets may also be dissolved in a small amount of water. If dissolved in water, stir the mixture well and drink all of it right away. Rinse your container with more water and drink the rinse liquid to be sure you receive the entire dose. Do not mix with acidic food or juices (such as orange juice, apple juice/sauce) since this may make the medicine taste bitter.

The dosage is based on your weight, medical condition, other medications, and response to treatment.

For the best effect, take this medication at evenly spaced times. To help you remember, take this medication at the same times every day.

It is very important to keep taking this medication (and other HIV medications) exactly as prescribed by your doctor. Do not take more or less of this drug than prescribed or stop taking it (or other HIV medicines) even for a short time unless directed to do so by your doctor. Skipping or changing your dose without approval from your doctor may cause the amount of virus to increase, make the infection more difficult to treat, or worsen side effects.