Read the Medication Guide provided by your pharmacist before you start using ocrelizumab and each time you get an infusion. If you have any questions, ask your doctor or pharmacist.

This medication is given by injection into a vein by a health care professional. It is given as directed by your doctor on a treatment schedule. The first 2 infusions are usually given 2 weeks apart. After that, an infusion is usually given once every 6 months. Follow your doctor's treatment schedule.

Infusion reactions (rarely fatal) may happen during the infusion of this drug and for up to 24 hours afterward. Your doctor may prescribe other medications (including acetaminophen, a corticosteroid such as methylprednisolone, an antihistamine such as diphenhydramine) to help prevent these side effects. Tell your doctor right away if you have any symptoms of infusion reactions such as rash, itching, trouble breathing, throat swelling/pain, tiredness, fever, fainting, flushing of the face, nausea, headache, dizziness, or fast heartbeat. Your doctor may slow down or stop your treatment for some time.