Take this medication by mouth as directed by your doctor, usually 4 times daily. It may be taken with food or meals if stomach upset occurs.

Carefully measure each dose using the dropper provided. If your medication comes in an oral dosing syringe, use the syringe to measure the dose. Do not use a household spoon because you may not get the correct dose. Do not inject the medication. The dose may be mixed with a small amount of water just before taking.

The dosage is based on your medical condition and response to treatment.

If you suddenly stop using this medication, you may have withdrawal symptoms (such as sweating, nausea, vomiting, restlessness). To help prevent withdrawal, your doctor may lower your dose slowly. Withdrawal is more likely if you have used opium for a long time or in high doses. Tell your doctor or pharmacist right away if you have withdrawal.

Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Do not increase your dose, take it more often, or use it for a longer time than prescribed. Properly stop the medication when so directed.

When used for a long time, this medication may not work as well and may require different dosing. Talk with your doctor if this medication stops working well.

Diarrhea can sometimes cause dehydration. It is important that you drink the proper amount of fluids and electrolytes to prevent this effect. Tell your doctor right away if you develop signs of dehydration (such as unusual decreased urination, unusual dry mouth/thirst, fast heartbeat, or dizziness/lightheadedness). You may also need to change to a bland diet during this time to reduce irritation to your stomach/intestines. Consult your doctor or pharmacist for more information.

Tell your doctor if your condition lasts or gets worse after 2 to 3 days of treatment.