Before use, clean the affected area with mild soap and water, rinse well, and pat dry.

To apply this product inside the anus, use the applicator tip/cap/nozzle, following all instructions in the product package, or use as directed by your doctor. Fill the applicator with medication from the container as directed. Gently insert the applicator tip just 1/2 to 1 inch (1.5 to 2.5 centimeters) inside the anus and apply in and around the anal opening as directed. Do not insert your finger or any part of the container into the anus, and do not insert the applicator tip/nozzle more than 1/2 to 1 inch (1.5 to 2.5 centimeters) inside the anus. Do not use your finger to apply this medication inside the anus. If you are using a single-use tube and applicator, discard after one use.

To apply the product to the outside of the anus only, apply a small amount to the affected area and rub in gently.

Do not cover the area with plastic or waterproof bandages unless directed to do so by your doctor. Covering the treated area may increase the absorption of the medication through the skin. This may improve how well the drug works, but it may also increase the risk of side effects.

Wash hands immediately after use. Avoid getting the product in your eyes, nose, ears or mouth. If the medication gets in these areas, rinse the area immediately with clean water.

Some brands are packaged in kits which have wipes. Before applying this medication, use the wipes as directed. The wipes are usually flushable, so discard the used wipes in the toilet.

This product is used as directed by your doctor, usually 3 to 4 times daily, or after each bowel movement. The dosage is based on your medical condition and response to treatment. Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same times each day.

Do not use more of this product, use it more often, or keep using it longer than prescribed by your doctor. If you have been using this medication for a long time or in high doses, do not suddenly stop using it without your doctor's approval. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased.

Inform your doctor if your condition does not improve or if it worsens after 1 to 2 weeks.