Take this medication by mouth with or without food as directed by your doctor, usually once daily or twice weekly.

The dosage is based on your age, weight, medical condition, and response to treatment.

For the best effect, take this antibiotic at evenly spaced times. If you are taking this medication daily, take it at the same time each day. If you are taking this medication on a weekly schedule, take it on the same days of the week and at the same time each day. Mark the days on the calendar when you need to take the medication.

Continue to take this medication (and other TB medications) until the full prescribed amount is finished, even if symptoms disappear. Stopping the medication too early or skipping doses may result in a return of the infection and cause the infection to be more difficult to treat (resistant).

Tell your doctor if your condition lasts or gets worse.