Take this medication by mouth at least 1 hour before or 2 hours after a meal as directed by your doctor, usually 1 or 2 times daily. Take this medication with a full glass of water (8 ounces/240 milliliters) unless your doctor directs you otherwise. If you need to take antacids, wait at least 1 hour after taking rifampin.

If you are unable to swallow the capsules, you may open the capsule and sprinkle the contents onto applesauce or jelly. Eat the entire mixture right away. Do not prepare a supply for future use.

If you are using the liquid form of this medication, shake the bottle well before each use. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

The dosage and length of treatment are based on your medical condition, weight, and response to treatment.

It is very important to keep using this medication (and other medications used to treat tuberculosis) exactly as prescribed by your doctor. Do not skip any doses.

For the best effect, use this antibiotic at evenly spaced times. To help you remember, use this medication at the same time(s) every day.

Continue to use this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.

Tell your doctor if your condition lasts or gets worse.