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TiclopidineMedical AlertYour condition can cause complications in a medical emergency. For information about enrolling in MedicAlert, call 1-888-633-4298 (US) or 1-800-668-1507 (Canada). WarningRarely, this medication has caused serious, sometimes life-threatening blood and immune disorders (agranulocytosis, aplastic anemia, neutropenia, thrombotic thrombocytopenic purpura-TTP). Symptoms may appear within the first few days after starting this medication. Get medical help right away if you have any of these serious side effects: difficulty speaking, weakness on one side of the body, seizures, red/purple pinpoint-sized spots on the skin, dark-colored urine, or yellowing eyes/skin (see also Side Effects section). Your doctor will be monitoring your blood counts before and regularly during treatment, especially the first 3 months of treatment. It is important that you keep all your medical and lab appointments. PrecautionsBefore taking this medication, tell your doctor or pharmacist if you are allergic to it; or to similar antiplatelet drugs (thienopyridines such as clopidogrel); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: current or past history of blood or immune disorders (thrombotic thrombocytopenic purpura, aplastic anemia, agranulocytosis, neutropenia), serious/active bleeding (such as bleeding stomach ulcers), bleeding/blood clotting disorders, liver disease, kidney problems. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Your doctor may instruct you to stop ticlopidine for 10 to 14 days before surgery. Follow your doctor's instructions carefully. This medication may cause stomach bleeding. Daily use of alcohol while using this medication will increase your risk for stomach bleeding. Limit alcoholic beverages. Ask your doctor or pharmacist about how much alcohol you may safely drink. Ticlopidine can make you more likely to get infections or may make current infections worse. Stay away from anyone who has an infection that may easily spread (such as chickenpox, COVID-19, measles, flu). Talk to your doctor if you have been exposed to an infection or for more details. Tell your health care professional that you are using ticlopidine before having any immunizations/vaccinations. Avoid contact with people who have recently received live vaccines (such as flu vaccine inhaled through the nose). While you are taking this medication, it may take longer than usual for bleeding to stop if you have a cut or injury. To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports. Older adults may be at greater risk for bleeding while using this drug. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. It is unknown if this drug passes into breast milk, but it may have undesirable effects on a nursing infant. Consult your doctor before breastfeeding. Side EffectsSee also Warning section. Diarrhea, stomach upset/pain, nausea, and vomiting may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: diarrhea that is severe or doesn't stop, bloody diarrhea, nausea/vomiting that doesn't stop, vomit that looks like coffee grounds, black stools, blood in the urine, bleeding from gums or nose, unusual weakness/tiredness, easy bruising/bleeding, mental/mood changes, loss of appetite, severe stomach/abdominal pain, signs of kidney problems (such as change in the amount of urine). This medication may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as sore throat that doesn't go away, fever, chills, cough). A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. |