Read the Patient Information Leaflet if available from your pharmacist before you start taking trametinib and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor, usually once daily. Take this medication on an empty stomach, at least 1 hour before or 2 hours after a meal. If you vomit, do not take another dose to catch up. Take your next dose at the regular time.

If you are using the tablets, swallow the tablets whole. Do not crush or break the tablets.

If your child is using the liquid form of this medication, read the Instructions for Use before you start giving trametinib and each time you get a refill. Gently swirl the bottle for 30 seconds to mix the solution prior to each dose. Learn how to carefully measure the dose using the bottle adapter and oral syringe provided. Do not use a household spoon because you may not get the correct dose. If you have any questions, consult your doctor or pharmacist.

The liquid form may also be given through a tube into the stomach (nasogastric or gastric tube). If you are giving this medication through a nasogastric or gastric tube, ask your health care professional for detailed instructions on how to give it.

The dosage is based on your medical condition and response to treatment. Children's dosage is also based on weight.

Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.

Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.

Since this drug can be absorbed through the skin and lungs and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication or breathe the dust from the tablets.