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Also indexed as:Eupatorium perfoliatum
Boneset: Main Image© Steven Foster
Botanical names:
Eupatorium perfoliatum

Side Effects

A small number of people experience nausea and/or vomiting when using boneset. The fresh plant, however, is more likely to cause this than the dried herb. Although potentially liver-damaging chemicals, called pyrrolizidine alkaloids, are found in some plants similar to boneset, the levels in boneset are minimal. There are no known reports of liver damage from taking boneset. Nevertheless, patients with liver disease should avoid boneset, and no one should take it consistently for longer than six months. Boneset is not recommended during pregnancy or breast-feeding. Boneset should not be used when a high fever (over 102 degrees F) is present.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.