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Also indexed as:Nicotinamide Adenine Dinucleotide
NADH: Main Image

Nicotinamide adenine dinucleotide (NADH) is the active coenzyme form of vitamin B3. It plays an essential role in the energy production of every human cell.

  • Reliable and relatively consistent scientific data showing a substantial health benefit.
  • Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
  • For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

This supplement has been used in connection with the following health conditions:

Used for AmountWhy
Chronic Fatigue Syndrome
10 mg daily2 stars[2 stars]
Supplementing with NADH may help your body produce more energy.
Parkinson’s Disease
5 mg twice per day2 stars[2 stars]
NADH—the active form of vitamin B3 in the body—has been shown to reduce symptoms and improve brain function in people with Parkinson’s disease.
Alzheimer’s Disease
10 mg per day 1 star[1 star]
A small, preliminary trial showed that oral NADH improved mental function in people with Alzheimer’s disease.
Depression
Refer to label instructions 1 star[1 star]
One study suggested that supplementing with NADH may help people with depression.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.