Read the Patient Information Leaflet if available from your health care professional before you start using hyaluronate and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

This medication is given by injection into the affected joint by a health care professional. It is given as directed by your doctor, usually once a week. The dosage is based on your medical condition and response to treatment. Extra fluid may need to be removed from the joint before the medication is injected.

Skin disinfectants that contain ammonium salts (such as benzalkonium chloride) should not be used to prepare the injection site. Hyaluronate should not be injected into a vein or artery because increased side effects may occur.

After receiving an injection of hyaluronate, you should avoid any activities that put stress on your knee (such as jogging, tennis, heavy lifting, standing on your feet for more than an hour) for 48 hours. Also, after the injection, you may experience increased pain and swelling in the knee at first. If the pain or swelling continues or worsens, talk to your doctor promptly.

It is important to have this medication injected on schedule. It may take up to 3 injections before the full benefits of this medication occur.

Tell your doctor if your condition lasts or gets worse.