Pantothenic Acid
Pantothenic acid, also called vitamin B5, is a water-soluble vitamin involved in the Kreb’s cycle of energy production and is needed to make the neurotransmitter acetylcholine. It is also essential in producing, transporting, and releasing energy from fats. Synthesis of cholesterol (needed to manufacture vitamin D and steroid hormones) depends on pantothenic acid. Pantothenic acid also activates the adrenal glands.1 Pantethine—a byproduct of pantothenic acid—has been reported to lower blood levels of cholesterol and triglycerides.
- Reliable and relatively consistent scientific data showing a substantial health benefit.
- Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
- For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.
Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.
For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.
This supplement has been used in connection with the following health conditions:
| Used for | Amount | Why |
|---|---|---|
High Cholesterol | 300 mg pantethine taken two to four times per day |  [3 stars] Pantethine, a byproduct of vitamin B5 metabolism, may help reduce the amount of cholesterol made by the body. |
High Triglycerides | 300 mg pantethine three times per day | [3 stars] Pantethine, a byproduct of pantothenic acid (vitamin B5), has been shown to lower triglyceride levels in several clinical trials. |
Rheumatoid Arthritis | 2,000 mg daily |  [2 stars] People with rheumatoid arthritis may be partially deficient in pantothenic acid. In one trial, taking pantothenic acid resulted in less morning stiffness, disability, and pain. |
Acne Vulgaris | Refer to label instructions |  [1 star] In a preliminary trial, taking panthothenic acid supplements and applying a topical cream improved moderate acne in two months and severe acne within six months.
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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.