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Adapalene-Benzoyl-Clindamycin

Precautions

Before using this product, tell your doctor or pharmacist if you are allergic to adapalene; or to benzoyl peroxide; or to clindamycin; or to lincomycin; or to vitamin A-related drugs (other retinoids such as isotretinoin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: eczema, certain intestinal problems (such as regional enteritis, ulcerative colitis, Crohn's disease, severe diarrhea with past antibiotic use).

This medication may make you more sensitive to the sun. Limit your time in the sun. Avoid tanning booths and sunlamps. Use sunscreen and wear protective clothing when outdoors. Tell your doctor right away if you get sunburned or have skin blisters/redness. Wait until your skin has completely recovered from a sunburn before using this product. Weather extremes such as wind or cold may also be irritating to the skin.

Avoid electrolysis, waxing, and chemical depilatories for hair removal on the treated areas while using this product.

Since this drug can be absorbed through the skin and may harm an unborn baby, women who are pregnant or who may become pregnant should not handle this medication.

Tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while using this medication. Adapalene may harm an unborn baby. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication.

It is unknown if this drug passes into breast milk when used on the skin. Consult your doctor before breastfeeding.

Side Effects

Skin redness, dryness, peeling, mild burning/stinging, swelling, or worsening of acne may occur during the first 4 weeks of using this product. These effects usually get better as you keep using it. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Your doctor may want you to use a moisturizer, use the product less often, or have you stop using it.

Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This medication may be absorbed into your bloodstream and very rarely cause a severe intestinal condition due to a bacteria called C. difficile. This condition may occur during treatment or weeks to months after treatment has stopped. Tell your doctor right away if you develop: diarrhea that doesn't stop, abdominal or stomach pain/cramping, blood/mucus in your stool.

If you have these symptoms, do not use anti-diarrhea or opioid products because they may make symptoms worse.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.