Read the Patient Information Leaflet if available from your pharmacist before you start using laronidase and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

This medication is given by injection into a vein as directed by your doctor, usually every week. The injection is given by a health care professional, usually over 3 to 4 hours. The dosage is based on your medical condition, weight, and response to treatment.

Infusion reactions may occur while you are receiving laronidase. Tell your doctor or nurse right away if any of these side effects occur: flushing, fever, headache, or abdominal pain. Your infusion may be slowed down or stopped depending on your symptoms. To prevent infusion reactions, your doctor may prescribe other medications 60 minutes before each infusion. Carefully follow your doctor's directions for all your medications. See also Warning section.

Use this medication regularly to get the most benefit from it. To help you remember, it may help to mark your calendar with a reminder.

Tell your doctor if your condition gets worse.